APS GUIDE

Building your own Artificial Pancreas,
we guide you through the journey.

Open-source DIY APS is powerful,
but it requires complex setup and learning that patients must handle themselves.

Explore the Setup Process

How does an Artificial Pancreas System (APS) work?

An artificial pancreas is a system that uses technology to replace the role of a stopped pancreas.
The core lies in a Closed-loop structure where 'Measure (Sensor) - Decide (App) - Inject (Pump)' continuously circulates.

Artificial Pancreas System circulation diagram: Connection flow between patient, glucose sensor, smartphone app (algorithm), and insulin pump

* The goal is for this entire process to be automated with minimal human intervention.

Step 1. Hardware Preparation

Connecting just any device won't work.
First, check the 'Golden Standard' combinations verified by the global community.

πŸ† Recommended Combination for Beginners (Golden Standard)

Galaxy S Series (Smartphone) + Dana-i (Pump) + Dexcom G6 (Sensor)

* This is the cleanest combination connecting via Bluetooth without additional communication equipment.

1. Android Phone

Brain of the System (Master)

iPhones (iOS) cannot use AndroidAPS due to background app execution restrictions.

βœ… Required Specs Checklist

  • OS: Android 9.0 (Pie) or higher
  • Model: Samsung Galaxy S series recommended
  • Warning: 'Android Go' editions are not supported

2. Insulin Pump

Execution Organ (Actor)

Receives commands from the smartphone to inject insulin. Bluetooth support is key.

βœ… Supported Models

  • Dana-i / Dana-RS (Recommended)
    Direct Bluetooth connection to phone
  • Medtronic / Combo
    Communication bridge like 'RileyLink' is required

3. Continuous Glucose Monitor

Detection Sensor (Sensor)

Transmits glucose values to the phone every 5 minutes. Developer app setup may be required instead of the official app.

βœ… Supported Models

  • Dexcom G6 / G7: Most stable
  • Libre 1, 2: Requires a separate transmitter
  • Note: Installing xDrip+ app is recommended

For more detailed compatibility information, please check the AndroidAPS Official Documentation .

Step 2. Building the App

This is the highest barrier to entry. Due to regulations, you cannot download it from the App Store.
Patients must become 'developers' and build an app tailored to their phones.

01

Prepare Materials

Copy (Fork) the source code (AndroidAPS) shared by global developers to your Github account.

02

Set up Tools

Just as cooking requires a kitchen, install Android Studio, a professional development program, on your PC.

03

Build the App

Open the imported code in Android Studio and click the 'Generate Signed APK' button to create the app file (.apk).

04

Install on Phone

Transfer the completed app file to your smartphone via USB and install it to finally see the icon.

Reality Check: Due to PC specs or Java version errors,
it takes an average of 3 days to 1 week for a non-major to complete this process alone.

Step 3. Tuning & Safety Settings

The app won't work perfectly right after installation.
For safety, you must pass a verification process similar to a 'driving test'.

1. Step-by-step Unlocking (Objectives)

For user safety, the artificial pancreas has its automated injection features locked initially.
You must solve 11 stages of quizzes and prove your actual pump operation ability to unlock the next stage.

Lv. 1
Simple Monitoring
Lv. 4
Open Loop
(Suggestions only)
Lv. 6~
Closed Loop Starts!
(Auto Injection)
Time required: It takes at least 1-2 weeks to enter Auto mode.

2. Input Your Body's Data

The AI needs reference values to make decisions. Much more precise values are required than at the hospital.

  • DIA (Duration of Insulin Action)
    How many hours insulin remains active in your body (usually 5-6 hours)
  • ISF (Insulin Sensitivity Factor)
    How much 1 unit of insulin lowers blood glucose
  • IC (Insulin to Carb Ratio)
    How many units of insulin are needed per 10g of carbs

3. Safety Limit Settings

Physical limits must be set to prevent device malfunction or excessive injection.

  • Max Bolus: Limit the maximum amount of insulin injected at once
  • Max Carb: Limit the maximum amount of carbs that can be logged
  • Hypo Alert: Must set alarms to wake you up if hypoglycemia occurs during sleep

Step 4. Principles of the Algorithm

How does the machine decide the insulin amount?
The key lies not in the present, but in 'predicting future glucose'.

IOB (Insulin On Board)

"Insulin still active in the body"
It calculates the residual amount already injected but not yet effective to prevent over-injection (hypoglycemia).

COB (Carbs On Board)

"Food not yet digested"
It calculates how much material is left in the stomach that will raise glucose, preparing insulin in advance.

Oref1 Algorithm Decision Process

Target Glucose (100)
Past
Present
Prediction (200↑) Future (in 30 mins)

"Current glucose is fine, but due to high COB (remaining food),
glucose is predicted to spike in 30 minutes."

πŸ‘‰ Command: Increase insulin delivery rate by 150%

Limitations of the Existing Algorithm

The DIY approach (Rule-based) relies solely on the formulas (ISF, IC) pre-entered by the user.
If variables not in the formula ariseβ€”such as 'menstrual cycle, stress, poor condition'β€”the prediction can be wrong.
This is exactly why a self-learning AI (GlucoUs) is needed.

Korea Standard

Koreans use the 'SMB Algorithm'

Because in a 'rice-based culture' with a high proportion of carbs,
the traditional basal adjustment (AMA) method cannot control glucose spikes.

What is SMB (Super Micro Bolus)?

Traditional Method (AMA)

Like opening a faucet a bit more,
it gradually increases the 'basal rate'.
β†’ Slow response time

SMB Method

Like firing a machine gun,
it delivers 'super micro boluses' rapidly.
β†’ Instantly suppresses sharp spikes

* This technology, based on the Oref1 library, is essential for high-carb Korean diets.

However, SMB is a 'Double-Edged Sword'

If the settings aren't perfect, there's a high risk of hypoglycemia.
This is exactly why GlucoUs's AI is necessary.

Category Existing DIY (SMB) GlucoUs (Next-Gen)
Operating Principle Rule-based
"If glucose is X, blindly inject Y"
RL-based (Reinforcement Learning)
"In this situation, injecting Y is optimal"
Core Issue Relies on user-input values (ISF)
If input is wrong, calculation is wrong
AI learns on its own
AI detects changes in the body
Meal Logging Manual input (Scale required) Camera photo (Auto volume calculation)

GlucoUs's Two Promises

We aren't just building a logging app.
We use technology to solve the biggest challenges in diabetes management: 'accurate meal measurement' and 'precise insulin control'.

1. Precise Meal Estimation

"A single photo is enough."

Vision AI technology analyzes the volume and mass of food in 3D. No more taking out a scale before meals or stressing over estimating by eye.

2. Next-Gen Insulin Therapy

"An algorithm that learns your body."

An AI based on Reinforcement Learning (RL) learns the user's glucose response patterns on its own, providing a precision insulin delivery algorithm optimized for the individual.

CORE TECHNOLOGY
Apparatus and Method for Predicting Insulin Resistance (Application No: 10-2023-0107245)
Reinforcement Learning-Based Blood Glucose Response Simulator Control System (Application No: 10-2025-0004963)

Roadmap to Freedom

GlucoUs's journey towards a fully artificial pancreas

2025

Foundation

  • Filed core patents for artificial pancreas
  • Completed MVP algorithm design

2026

Validation (NOW)

  • β€’ Launched beta of meal management app
  • β€’ Officially launched diabetes awareness simulator
  • β€’ Secured clinical data for artificial pancreas algorithm

2027

Expansion

  • β€’ SaMD (Software as a Medical Device) clearance
  • β€’ Expansion into the global market (North America)

2028~

Completion

  • β€’ Commercialization of fully automated on-device AI artificial pancreas

Does it feel too complicated?

We know the moment the joy of eating becomes a chore.
With GlucoUs, there is no complex coding. Just one camera shot
analyzes nutrients, and AI predicts your glucose.

Meet the GlucoUs Kit

* Currently recruiting beta testers